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Higher melanin levels result in darker skin tones, while lower melanin levels result in lighter skin tones

Interaction between p53 N terminus and core domain regulates specific and nonspecific DNA binding

PLoS ONE 9 , e104519 (2014)

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Materials and methods Reagents tert-Butyl hydroperoxide, cumene hydroperoxide, hydrogen peroxide, ferrostatin-1, cyclosporine A, GSH, GSSG, and MG132 were from Sigma